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Evaluation of Job Applicants Using Neuroscience
Bank, Tomáš ; Beran, Vítězslav (referee) ; Szőke, Igor (advisor)
This thesis deals with the possibility to evaluate cognitive and emotional traits and their relations to job positions and functions. The basis is to create a set of tests which could be used during a hiring procedure while deciding among candidates. It also suggests how to classify users based on a set of tests and thereby provide support in choosing the right job. The thesis gives a brief outlook of individually tested traits, describes a proposal of a web application and its implementation, describes implementation of neural network classifier and presents obtained results.
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Gen expresion of high affinity choline transporter in mouse model of Alzheimer's disease
Kurfürst, Helena ; Doležal, Vladimír (advisor) ; Krištofíková, Zdena (referee)
: Choline is being used in all mammalian cells as a precursor for synthesis of a major phospholipide phosphatidylcholine and as a donor of acetyl residues. Cholinergic neurons in addition require choline to synthesize neuromediator acetylcholine. The ability of cells to create choline via de novo synthesis is limited and therefore they need to transport choline from extracellular space. Limited availability of choline in brain leads specifically to diminished function of cholinergic neurons and in general to impaired reparation of biological membranes. Dysfunctions of cholinergic signaling in brain is characteristic for Alzheimer's disease. Aim of this work was to investigate whether gene and protein expression of high- affinity cholinergic transporters is altered in 5-6 months old APPswe/PS1dE9 mouse model of Alzheimer's disease. Expression of specific high-affinity cholinergic transporter CHT1 (responsible for transport of choline to be used for acetylcholine synthesis) and putative high-afinity choline transporter CTL1 (generally present in all cells and related to high affinity choline transport for phospholipide synthesis) in cerebral cortex was measured. Compared to non-trangenic littermates, no changes in the expression of both genes were detected at either mRNA (quantitative PCR) or protein...
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Specifics of teaching of French as a foreign language of adolescents and adults students at the beginner level A1
Vlasatá, Adéla ; Machleidtová, Silva (advisor) ; Müllerová, Eva (referee)
The aim of this thesis is to analyze, from general didactic perspective, specifics of French language teaching of adolescent as well as adult students at the beginner level. More specifically, socalled FLE teaching within informal educational environment of a particular language school in Prague is examined. In order to do so, this thesis is divided into two sections. In the first theoretical section, the compilation method is employed, resulting in detailed analysis of selected didactic themes related to the defined aim of the thesis. The second, supporting section consists of specially compiled survey analysis, which focuses on themes covered at the first theoretical part. It is worth noting that perspectives of students are captured as a result of the survey analysis. The major contribution of this thesis is a comprehensive theoretical and practical view on not yet separately compiled methodology of teaching of French language of beginning, predominantly adult students, in the context of Czech informal educational environment.
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Word, speech and language. Interdisciplinary field of theology and neuroscience.
Tomášek, Martin ; Vogel, Jiří (advisor) ; Vik, Dalibor (referee)
74 Abstract Logos is the multi-meaning term accompanying philosophy from the earliest authors. In general, the term logos has historically had two main groups of meanings. The first group concerns speech (word, speech, sentence…) and the second group of meanings concerns reason (thought, reason, mind, thinking…). In philosophical-theological thinking the second group passes into the idea of reason transcending man - "divine" or "world reason". The theoretical basis of the duality of both speech and reason was postulated by analytical philosophy. As Humboldt was already convinced, thinking was always associated with language, speech was an organ of creating thoughts. Pneumatological philosopher Ebner says: man is by nature "the Spirit who posseses the word," "there is no reason without the Word," and "reason is speech, logos". Within the philosophy of language Wittgenstein argues: "the boundaries of my language create the boundaries of my world," and "a sentence is an image of reality". Fodor's linguistic works on the inner language of thought ("Mentalese") and especially Chomsky's theory of the existence of a structure for "universal grammar" in the human brain provide preconditions for the search of such a structure. Neuroscientific research confirms these assumptions. Structures specialized for speech...
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Evaluation of Job Applicants Using Neuroscience
Bank, Tomáš ; Beran, Vítězslav (referee) ; Szőke, Igor (advisor)
This thesis deals with the possibility to evaluate cognitive and emotional traits and their relations to job positions and functions. The basis is to create a set of tests which could be used during a hiring procedure while deciding among candidates. It also suggests how to classify users based on a set of tests and thereby provide support in choosing the right job. The thesis gives a brief outlook of individually tested traits, describes a proposal of a web application and its implementation, describes implementation of neural network classifier and presents obtained results.
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Theological Aspects of Coaching
Macek, Karel ; Ovečka, Libor (advisor) ; Mašek, Vojtěch (referee)
Coaching is a modern tool for personal development with many advantages and successful applications. However, some concerns arise from the religious and ethical perspectives. Links to esoterics and New Age have been proclaimed by leaders of coaching schools that operate in the Czech Republic. Moreover, a survey has indicated that ethical limits of Czech coaches are more liberal than the official position of the Catholic Church. Thus, for a Catholic Christian, the coaching is promising as well as questionable. Biblical texts, as well as the facts from the subsequent history of Church, indicate many similarities: Christianity has exhibited marks of coaching since the very beginnings. On the other hand, most of the coaching schools deny God, absolute truth, or the concept of sin. An appropriate approach how to address this tension is a reflection of anthropological fundaments. Analyzing sincerely one of the coaching schools (Neuroleadership), we can conclude that all of them have clear counterparts in the Christian doctrine. In spite to this positive conclusion, it is necessary to be cautious when facing practical ethical dilemmas. A wise application of the coaching approach can be helpful also in the spiritual direction. Powered by TCPDF (www.tcpdf.org)
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Specifics of teaching of French as a foreign language of adolescents and adults students at the beginner level A1
Vlasatá, Adéla ; Machleidtová, Silva (advisor) ; Müllerová, Eva (referee)
The aim of this thesis is to analyze, from general didactic perspective, specifics of French language teaching of adolescent as well as adult students at the beginner level. More specifically, socalled FLE teaching within informal educational environment of a particular language school in Prague is examined. In order to do so, this thesis is divided into two sections. In the first theoretical section, the compilation method is employed, resulting in detailed analysis of selected didactic themes related to the defined aim of the thesis. The second, supporting section consists of specially compiled survey analysis, which focuses on themes covered at the first theoretical part. It is worth noting that perspectives of students are captured as a result of the survey analysis. The major contribution of this thesis is a comprehensive theoretical and practical view on not yet separately compiled methodology of teaching of French language of beginning, predominantly adult students, in the context of Czech informal educational environment.
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Gen expresion of high affinity choline transporter in mouse model of Alzheimer's disease
Kurfürst, Helena ; Krištofíková, Zdena (referee) ; Doležal, Vladimír (advisor)
: Choline is being used in all mammalian cells as a precursor for synthesis of a major phospholipide phosphatidylcholine and as a donor of acetyl residues. Cholinergic neurons in addition require choline to synthesize neuromediator acetylcholine. The ability of cells to create choline via de novo synthesis is limited and therefore they need to transport choline from extracellular space. Limited availability of choline in brain leads specifically to diminished function of cholinergic neurons and in general to impaired reparation of biological membranes. Dysfunctions of cholinergic signaling in brain is characteristic for Alzheimer's disease. Aim of this work was to investigate whether gene and protein expression of high- affinity cholinergic transporters is altered in 5-6 months old APPswe/PS1dE9 mouse model of Alzheimer's disease. Expression of specific high-affinity cholinergic transporter CHT1 (responsible for transport of choline to be used for acetylcholine synthesis) and putative high-afinity choline transporter CTL1 (generally present in all cells and related to high affinity choline transport for phospholipide synthesis) in cerebral cortex was measured. Compared to non-trangenic littermates, no changes in the expression of both genes were detected at either mRNA (quantitative PCR) or protein...
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